Roma will have to do without influential skipper Francesco Totti when they host Manchester United in the UEFA Champions League quarter-finals game on Tuesday. The veteran striker picked up a thigh injury during Saturday's 1-1 Serie A draw at Cagliari, which saw him net the equalizer for the Giallorossi. "At the end of yesterday's encounter, Francesco Totti complained of a pain in the flexor of his left thigh,” a statement read on Roma's official site. "In the morning of Sunday March 30 he was subjected to tests that highlighted a muscular injury in the cavity of the left thigh flexor. "The player will have to have a period of rest and the situation will be monitored over the next few days." Totti has 14 Serie A goals for Roma so far this season, and his absence will be a blow for Luciano Spalletti's team.