Russia hit ISIS targets with Kalibr cruise missiles launched from the kilo class submarine 'Rostov-on-Don', the Russian Defense Minister Sergey Shoigu said on Tuesday. Russian warplanes have destroyed 140 ISIS targets in Syria, Sergey Shoigu said. Russian air forces have liberated 40 town from terrorists in the Northern Syria, he added. Russian warplanes launched airstrikes against Islamic State (ISIS) and other militant groups at the request of Syrian President Bashar Assad on September 30. Since the beginning of the air campaign, Russian Aerospace Forces have carried out around 1,800 sorties, destroying some 2,700 terrorist targets, according to the General Staff. Several hundreds of militants have been killed, and dozens of command centers and depots have been destroyed.