The U.S. death toll from COVID-19 has topped 600,000 as the vaccination drive has decreased daily cases and deaths. That's according to a tally by Johns Hopkins University. The number of lives lost is greater than the population of Baltimore or Milwaukee. It is about equal to the number of Americans who died of cancer in 2019. With the advent of the vaccines, COVID-19 deaths per day in the U.S. have plummeted to an average of 340 from a high of more than 3,400 in mid-January. Cases are running at 14,000 a day on average, down from a quarter-million per day during the winter. Worldwide, the COVID-19 confirmed death toll stands at 3.8 million. The actual totals in the U.S. and around the globe are thought to be significantly higher, with many cases overlooked or possibly concealed by some countries.